Thus, despite some encouraging results, more research is required for developing a valuable anti diabetic therapy using pancreatic alphaamylase inhibitors of plant origin. Antidiabetic activity of heart wood of pterocarpus marsupium. Antidiabetic effect was evaluated in alloxaninduced diabetic model 2023. Hypoglycemic activity of inflorescence of borassus. Evaluation of antidiabetic activity of leaves and fruits of ficus religiosa linn. Evaluation of antidiabetic activity of leaves and fruits of.
Evaluation of in vitro anti diabetic activity of selected plant extracts sindhu. Boerhavia diffusa bd is a plant of rasayana category as per ayurvedic claims. Pulla reddy college of pharmacy, mehdipatnam, hyderabad 500 028. The results showed that the plant extracts were a rich source of phytoconstituents. Current research journal of biological science, 22.
Antidiabetic activity of boerhaavia diffusa l effect on hepatic key enzymes in experimental diabetes article in journal of ethnopharmacology 911. A drugdevelopment programme should be undertaken to develop modern drugs with. Suvagiya 5 faculty of pharmaceutical sciences, pacific university 1, udaipur, rajasthan, india. Antibacterial activity of some indian medicinal plants. Fryxell malvaceae, known as malva preta, is a small shrub. Evaluation of in vitro anti diabetic activity of selected. Antidiabetic herbal formulations are considered to be more effective for treatment of diabetes. The butanol extract produced maximum anti diabetic activity and is higher than the hypoglycemic activity of glibenclamide in the diabetic rats. The effect of petroleum ether and methanol crude extracts and phytoconstituents from b. The anti diabetic activity of four extracts prominently reduces blood glucose levels in stznicotinamide induced diabetic rats. International journal of engineering technology, management and applied sciences. Evaluation of antibacterial activity of phytoconstituents. The extract was tested for antiinflammatory activity using carrageenan induced paw edema in albino rats.
Blood glucose levels and body weights of control and diabetic mice were monitored. A significant decrease in blood glucose and a significant increase in plasma insulin levels were observed in normal and diabetic rats treated with aqueous solution of boerhavia diffusa l. The present study is aimed at evaluating the antidiabetic activity of chloroform extract of boerhaavia diffusa leaves on. In vitro antidiabetic activity of leaves and seeds of. The antidiabetic activity of four extracts prominently reduces blood glucose levels in stznicotinamide induced diabetic rats. Antidiabetic activity of boerhaavia diffusa l effect on hepatic key. Determination of in vitro antidiabetic effects of zingiber.
Screening the two extracts for antibacterial activity against shigella flexneri, pseudomonas fluorescens. Boerhavia diffusa is originated throughout the warmer parts of the country upto an altitude of 2000 metre in the himalayan region. Antiinflammation, analgesic and antipyretic properties. Anti diabetic medicinal plants used for diabetes mellitus maryam rahimi department of horticultural science, university of zabol, iran abstract diabetes mellitus is a group of metabolic diseases characterized by high blood sugar glucose levels, that result from defects in insulin secretion, or action, or both. The animals were fasted for 16h before experimentation but allowed. The investigation established some pharmacological evidence to support the folklore claim that it is used as an anti diabetic agent23. Azardirachta indica it belongs to family meliaceae popularly known as neem.
Antidiabetic activity of helicteres isora root sama venkatesh1, g. The ethanolic extract of the fruit, at a dosage of 250 mgkg body weight, was found to exert a more pronounced antidiabetic activity than a 100mgkg body. Anti diabetic effect was evaluated in alloxaninduced diabetic model 2023. The methanolic whole plant extract at high dose 500 mgkg exhibited significant antihyperglycemic activity than whole plant extract at low dose 300 mgkg in diabetic rats. The main objective of this work is to evaluate the in vitro anti diabetic activity of methanolic. Diabetes mellitus is known as a group of chronic metabolic diseases characterized by rise in blood glucose level due to defects in insulin secretion, insulin action, or both. Determination of in vitro antidiabetic effects of zingiber officinale roscoe 603 glucose diffusion inhibition the potential of ginger rhizome extracts to inhibit glucose diffusion into the external solution was investi gated at set time intervals gallagher et al. An overview on antidiabetic medicinal plants having insulin. Infectious diseases pose serious problems to health and they are main causes of morbidity and mortality worldwide 9. Anti diabetic medicinal plants used for diabetes mellitus g arumugam1, p manjula2, n paari2 1 2 doi. Anti diabetic medicinal plants open access journals.
Antidiabetic activity of medicinal plants and its relationship with their antioxidant. It was extracted up to one week with daily 2 hours stirring with a mechanical stirrer. Jul 14, 20 the phytoconstituents such as catechin, epicatechin, and ellagic acid were reported for their in vivo and in vitro antidiabetic activity. Journal of acute disease 20196200 contents lists available at sciencedirect journal of acute disease journal homepage. Streptozotocin induced type 2 diabetic model is a widely used and validated animal model as the induced diabetic condition has close resemblance to that in humans. Plant extracts, anti diabetic, anti cancer, anti oxidant background type 2 diabetes has become a major health problem in both developed and developing countries. Oral treatment of aetpb using rat oral needle at 100 and 200. In vivo and in vitro antidiabetic activity of terminalia. Antidiabetic activity of boerhaavia diffusa l effect on. The database describes medicinal plants having anti diabetic activity with other related information including relevant references. Dglucopyranoside isolated from ethanolic extract of aerial parts of plant. Catechin showed significant antidiabetic activity in stzinduced diabetic rats, and docking studies confirmed it might be due to activation of insulin receptor and agonist action on peroxisome proliferator. Since alpha amylase is the enzyme responsible for hyperglycemia by inhibiting its activity the above mentioned plants are having anti diabetic properties.
Achika1, david ebuka arthur1, igelige gerald1, adebiyi adedayo2. More number of plant and plant products have been scientifically tested and reported to posses anti diabetic activity 2635 examples of herbal medicines with proven anti diabetic activity plant part used. Plant extracts, antidiabetic, anticancer, antioxidant background type 2 diabetes has become a major health problem in both developed and developing countries. The present study was carried out to evaluate the antidiabetic activity of vinca rosea methanolic whole plant extracts in alloxan induced diabetic rats for 14 days.
Phytochemical and pharmacological profile of leucas. The present study was designed to investigate the glucose uptake of antidiabetic activity crude nhexane,ethanol, methanol and aqueous leaf extracts of cardiospermum halicacabum. After 7 days the extract was filtered through muslin cloth and marc was discarded. In vitro antidiabetic activity of cardiospermum halicacabum leaves extracts by stalin. Antidiabetic activity of terminalia catappa leaf extracts ijpt. It is reported that the plant shows good anti depressant, antioxidant, anti inflammatory and anti. In vitro antidiabetic activity of lea tidiabetic activity of leaves and. In the present investigation, the antidiabetic and antihyperlipidemic effects of methanolic extract of b. Evaluation of antidiabetic activity of leaves and fruits. Anti diabetic activity of terminalia catappa leaf extracts ijpt. Methanol extract has shown estimable decrease of blood glucose level p phytoconstituents and related medicinal properties of plants in the asteraceae family jonathan i. Kalaiarasan 1meenakshi chandrasekaran arts and science college, pattukkottai 614 601.
Antidiabetic and antihyperlipidemic activity of roots of. Rats were randomly divided into 6 groups containing 8 rat in each group. Antidiabetic activity of the leaves extracts of wrightia. The clinical efficiency of many existing antibiotics is being threatened by the emergence of multidrug resistant. Induction and screening of antidiabetic activity using alloxan.
Methanol extract has shown estimable decrease of blood glucose level p with glibenclamide. Antidiabetic activity of polyherbal formulation on. In vitro antidiabetic activity of leaves and seeds of boerhavia diffusa in vitro alpha amylase inhibitory activity in vitro. There was a dosedependent increase in percentage inhibitory activity against alphaamylase enzyme. It is a perennial, spreading hogweed, commonly grown abundantly in waste places, ditches. Oral administration of the ethanol extract, juice and oil of allium sativum has remarkably blood sugar lowering effect in normal and alloxaninduced diabetic rats. Diabetes is a chronic metabolic disorder of proteins, fats and carbohydrate, affecting a large number of world population in the world 1. Effect of chronic administration of boerhaavia diffusa linn. A boerhavia coccinea, b boerhavia elegans, c boerhavia erecta, d boerhavia repens, e boerhavia diffusa. Antioxidants thus play an important role to protect the human body against damage by reactive oxygen species lollinger. The present study was designed to investigate the glucose uptake of antidiabetic activity crude nhexane,ethanol, methanol and aqueous leaf. Detail study on boerhaavia diffusa plant for its medicinal. Singh 2 1 department of pharmacolog y, goenka college of pharmac, nh11, p. Hypoglycemic activity of inflorescence ofborassus flabellifer extracts on blood glucose levels of streptozocininduced diabetic rats pradeep goyal, 1, anil agarwal 1, lakshminarasimhaiah 1 and g.
In the genus boerhavia, preclinical evaluation of antidiabetic and antihyperlipidemic activity was reported only for b. The database also contains detailed information about the. These findings suggest that anti diabetic property of trichodesma indicum l. Type 2 diabetes was induced in rats by streptozotocinnicotinamide 65 mgkg110 mgkg. Phytochemical and biological importance of boerhavia. Free radicals have been implicated in the causation of several diseases such as liver cirrhosis, atherosclerosis, cancer, diabetes, etc. The present study was aimed to investigate in vivo, in vitro antidiabetic activity of aqueous extract of terminalia paniculata bark aetpb and characterize its possible phytoconstituents responsible for the actions. Here, we describe a database containing information for anti diabetic plants and their use. Phytochemical and in vitro antidiabetic activity of. The anti hyperglycemic effect of the methanolic extract of the leaves of g. Antibacterial activity and phytochemical screening of ethanolic extracts obtained from selected sudanese medicinal plants. Nair1, vaibhavi kavrekar1, anshu mishra1 1 department of biotechnology, mount carmel college, bangalore, karnataka, india abstract. Phytochemical screening and in vitro bioactivities of the extracts of.
Therefore it is obvious that the fractionation with butanol has enriched the active principles. Evaluation of phytochemical and antimicrobial activities of. Boerhavia diffusa punarnava is one of the famou human ailments as mentioned in ayurveda, charaka known to have medicinal properties. Phytochemical and pharmacological evaluation of abelmoschus. The present research is carried out to evaluate the anti diabetic activity of abelmoschus esculentus. Antidiabetic activity of polyherbal formulation on alloxan. Evaluation of antidiabetic activity of the polyherbal formulation 16.
Induction and screening of anti diabetic activity using alloxan. In conclusion, this paper has presented a list of anti diabetic plants used in the treatment of diabetes mellitus. The antihyperglycemic effect of the methanolic extract of the leaves of g. The extract exhibited effect in a dose dependent manner. Antiinflammatory potential of flavones glycoside chrysoeriol4. Anti diabetic activity of dodonaea viscosal leaf extracts p. Antidiabetic activity of boerhaavia diffusa l effect on hepatic key enzymes in experimental diabetes. Phytochemical screening and in vitro bioactivities of the extracts of aerial part of. Methanol extract showed higher antioxidant, thrombolytic activity and less cytotoxic activity than those of nhexane and ethyl acetate extracts of b. Evaluation of anti diabetic activity of the polyherbal formulation 16. The diabetic animals were randomly divided into eight groups with 8 rats in each group and treated as follows for 14 days continuously orally.
In the present study activities of liver enzymes such as glucokinase, glucose. Antidiabetic activity of heart wood of pterocarpus. Evaluation of phytochemical and antimicrobial activities. The identification of phytoconstituents and assay of antioxidant, thrombolytic. Antidiabetic effect of ethanolic leaf extract of phyllanthus. Allium sativum alliaceae antihyperglycemic activity of ethyl ether extract at 0. Potential antidiabetic herbal medicines html full text. A novel anti hyperglycemic amino acid has been extracted and purified from fenugreek seeds 4hydroxyleucine which reportedly increases glucoseinduced insulin release. Plant extracts were used in concentration ranging from 50500 gml and 500 l of 16 mm sodium. An overview on antidiabetic medicinal plants having.
Besides some less promising effects exhibited by this plant includes nonteratogenic, antioxidant, anti viral activity against plant. Among the bioactivities, antioxidant activity was the most notable compared to the positive control and thus could be a potential rich source of. Antidiabetic activity of heart wood of pterocarpus marsupium roxb. The present research is carried out to evaluate the antidiabetic activity of abelmoschus esculentus. Antidiabetic activity of dodonaea viscosal leaf extracts p.
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